DNA PolymeraseBeta, Human, 重组蛋白 (His) TMPJ-00792

Product Introduction
Bioactivity


英文名: DNA PolymeraseBeta Protein, Human, Recombinant (His)

描述: Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. It conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. The activity cannot be affected by Aphidicolin, which is an inhibitor of DNA polymerase β.

存储条件: store at low temperatureLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途