MAdCAM-1, Human, 重组蛋白 (Avi & His), Biotinylated TMPJ-01150
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 μg | TMPJ-01150 | ¥6,130.00 | 询底价 |
20 μg | TMPJ-01150 | ¥2,260.00 | 询底价 |
Product Introduction
Bioactivity
英文名: MAdCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
描述: Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of proteins. The Ig domains of MAdCAM-1 are critical to alpha (4) beta (7) binding, and the mucin domain has activity in L Selectin binding. MAdCAM-1 expression is up-regulated by TNF-alpha and IL 1 beta. Mucosal addressin cell adhesion molecule (MAdCAM-1) plays a pivotal role in T-lymphocyte homing to the gut. MAdCAM 1 expression is also dramatically increased in chronic inflammatory and disease states, including inflammatory bowel disease (Crohn’s disease and ulcerative colitis), sclerosing cholangitis, and diabetes, and may play an important role in these conditions.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: MACAM 1 | MACAM-1
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途