ZBP1, Human, 重组蛋白 (His) TMPJ-01328
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 μg | TMPJ-01328 | ¥1,170.00 | 询底价 |
500 μg | TMPJ-01328 | ¥12,100.00 | 询底价 |
1 mg | TMPJ-01328 | ¥17,400.00 | 询底价 |
50 μg | TMPJ-01328 | ¥3,470.00 | 询底价 |
Product Introduction
Bioactivity
英文名: ZBP1 Protein, Human, Recombinant (His)
描述: Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of viral and bacterial DNA from by the host's innate immune system. It plays a role in host defense against tumors and pathogens. ZBP1 Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: DLM-1 | ZBP 1 | DLM 1 | ZBP-1
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途