RGMA, Human, 重组蛋白 (His & Avi) TMPK-00278

Product Introduction
Bioactivity


英文名: RGMA Protein, Human, Recombinant (His & Avi)

描述: Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS).  RGM is expressed in pathogenic Th17 cells and induces neurodegeneration by binding to neogenin.

存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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