FGFR3 alpha (IIIc), Human, 重组蛋白 (His & Avi), Biotinylated TMPK-00386

Product Introduction
Bioactivity


英文名: FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

描述: Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.

存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

关键字: JTK-4 | CEK 2 | FGFR 3 | CD 333 | FGFR-3 | CEK-2 | CD-333 | JTK 4

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