PDGF R beta/CD140b, Human, 重组蛋白 (His & Avi) TMPK-00421

Product Introduction
Bioactivity


英文名: PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)

描述: PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.

存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

关键字: JTK 12 | PDGFR2 | PDGFR-1 | PDGFR-beta | JTK-12 | PDGF R b | PDGFR-b | PDGFR 2 | PDGFR 1

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途