Granzyme B/GZMB, Human, 重组蛋白 (His) TMPY-00817
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | 价格 | 操作 |
---|---|---|
500 μg | ¥22,510.00 | 询底价 |
200 μg | ¥11,130.00 | 询底价 |
100 μg | ¥6,530.00 | 询底价 |
50 μg | ¥3,820.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Granzyme B/GZMB Protein, Human, Recombinant (His)
描述: Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of GZMB have been identified including the key substrate caspase-3, ICAD, and Bid. GZMB is suggested to protect the host by lysing cells bearing on their surface 'nonself' antigens such as bacterial and viral infected-cells and tumor cells and accordingly plays an essential role in immunosurveillance.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: CTLA 1 | CTLA-1 | CTSGL-1 | CTSGL 1 | CGL 1 | granzyme B
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途