p38 gamma/MAPK12, Human, 重组蛋白 (His & GST) TMPY-04429

Product Introduction
Bioactivity


英文名: p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

描述: ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/threonine kinase that acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 2 to 3 substrates each. MAPK12 is required for the normal kinetochore localization of PLK1, prevents chromosomal instability, and supports mitotic cell viability. MAPK12-signaling is also positively regulating the expansion of transient amplifying myogenic precursor cells during muscle growth and regeneration.

存储条件: store at low temperatureLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

关键字: MAPK-12 | MAPK 12 | PRKM 12 | PRKM-12 | SAPK 3 | ERK 6 | ERK-3 | ERK 3

p38 gamma/MAPK12, Human, 重组蛋白 (His & GST) TMPY-04429信息由TargetMol中国为您提供，如您想了解更多关于p38 gamma/MAPK12, Human, 重组蛋白 (His & GST) TMPY-04429报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途