表大戟二烯醇 TN1006
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 514-46-5 | ¥2,480.00 | 询底价 |
1 mL | 514-46-5 | ¥1,770.00 | 询底价 |
5 mg | 514-46-5 | ¥1,670.00 | 询底价 |
50 mg | 514-46-5 | ¥5,960.00 | 询底价 |
1 mg | 514-46-5 | ¥682.00 | 询底价 |
25 mg | 514-46-5 | ¥4,180.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Tirucallol
描述: Tirucallol 是一种四环三萜,分离自Euphorbia lacteal 乳胶。它能够抑制小鼠模型中的耳部水肿,并阻碍脂多糖刺激的巨噬细胞中亚硝酸盐的产生,具有局部消炎作用。
体外活性: The effect of CMG neutral extract (25-200 microg/ml) and Tirucallol (0.1-100 microM) on the following: 1) the expression of adhesion molecules (VCAM-1 and ICAM-1) by Cell ELISA and 2) the attachment of monocytes (U937 cells) in TNF-alpha stimulated Human Aortic Endothelial Cells (HAEC) by Adhesion assay. The impact of treatment with CMG neutral extract and Tirucallol in NFkB phosphorylation was also examined by a cell-based ELISA kit. Both CMG extract and Tirucallol inhibit significantly VCAM-1 and ICAM-1 expression in TNF-alpha-stimulated HAEC. They also inhibit significantly the binding of U937 cells to TNF-alpha-stimulated HAEC and attenuate the phosphorylation of NFkB p65.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 4.27 mg/mL (10 mM)
关键字: antiinflammatory | triterpene | Euphorbia | tetracyclic | inhibit | Tirucallol | Inhibitor | lacteal | latex
相关产品: Kobusin | Curvularin | 2-Methoxystypandrone | Diallyl disulfide | 7-Nitroindazole | Myricetin 3-O-galactoside | Chamigrenal | Friedelin | Shizukaol B | S-(2-aminoethyl) Isothiourea (dihydrobromide)
相关库: Terpene Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Human Endogenous Metabolite Compound Library Plus | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | NO PAINS Compound Library | Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途