1-咖啡酰奎宁酸 TN1051

Product Introduction
Bioactivity


英文名: 1-Caffeoylquinic acid

描述: 1-Caffeoylquinic acid 是一种有效的NF-κB 抑制剂，对 p105 的 RH 结构域显示高结合亲和力，Ki= 0.002 μM，结合能为 1.50 Kcal/mol。它抑制PD-1/PD-L1相互作用。它具有抗氧化应激能力。

体外活性: Thirteen phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, 1-Caffeoylquinic acid, 5-p-coumaroylquinic acid, isoorientin-2'-O-rhamnoside, isoorientin, orientin-2'-O-rhamnoside, orientin, 1-p-coumaroylquinic acid, vitexin-2'-O-rhamnoside, isovitexin-2'-O-rhamnoside, vitexin and isovitexin) were identified in T. hemsleyanum leaves for the first time, and six of them were quantified using a combination of LC-QTOF-MS and LC-QqQ-MS techniques. It was found that 80% methanol extract exhibited the highest antioxidant activities.

存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 9 mg/mL (25.4 mM)


关键字: inhibit | NF-κB | Nuclear factor-kappaB | Nuclear factor-κB | 1-Caffeoylquinic acid | Inhibitor | 1Caffeoylquinic acid | 1 Caffeoylquinic acid

相关产品: CHPG sodium salt | Kushenol C | Morusin | Pinoresinol | Rubioncolin C | Bakkenolide IIIa | Cyclo(his-pro) | Tomatidine | Aurantiamide | Heliangin

相关库: Antioxidant Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Transcription Factor-Targeted Compound Library | Anti-Cancer Compound Library | NF-κB Signaling Compound Library | Anti-Lung Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Traditional Chinese Medicine Monomer Library | PPI Inhibitor Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途