女贞苷G13 TN1074

Product Introduction
Bioactivity


英文名: GL3

描述: GL3 是一种基于苯基乙醛醇和甲基油苷的衍生物，也是苦瓜种子的主要成分。

体外活性: We show here that trichome initiation is triggered within 4 h of the induction of the GLABRA3 (GL3) basic helix-loop-helix transcription factor. Within this developmental window, GL3 binds to the promoters of at least three genes previously implicated in the development and patterning of trichomes (GL2, CAPRICE, and ENHANCER OF TRIPTYCHON AND CAPRICE1) and activates their transcription. The in vivo binding of GL3 to the promoters of these genes requires the presence of the R2R3-MYB factor GL1, supporting a model in which a GL3-GL1 complex is part of the trichome initiation enhanceosome. In contrast, GL3 is recruited to its own promoter in a GL1-independent manner, and this results in decreased GL3 expression, suggesting the presence of a GL3 negative autoregulatory loop. In support of genetic analyses indicating that ENHANCER OF GL3 (EGL3) is partially redundant with GL3, we show that EGL3 shares some direct targets with GL3. However, our results suggest that GL3 and EGL3 work independently of each other.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 22.5 mg/mL (20.97 mM)


关键字: inhibit | GL 3 | GL-3 | Inhibitor | GL3

相关库: Terpene Natural Product Library | Selected Plant-Sourced Compound Library | Natural Product Library for HTS | Natural Product Library

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