2-羟甲基蒽醌 TN1213

Product Introduction
Bioactivity


英文名: 2-(Hydroxymethyl)anthraquinone

描述: 2-(Hydroxymethyl)anthraquinone 是光可清除保护基团，在结构上可以阻碍性信息素释放。

体外活性: The growth-inhibiting activity of Tabebuia impetiginosa Martius ex DC dried inner bark-derived constituents against Helicobacter pylori ATCC 43504 was examined using paper disc diffusion and minimum inhibitory concentration (MIC) bioassays. The activity of the isolated compounds was compared to that of the commercially available anti-Helicobacter pylori agents, amoxicillin, metronidazole, and tetracycline. The biologically active components of Tabebuia impetiginosa dried inner bark (taheebo) were characterized by spectroscopic analysis as 2-(Hydroxymethyl)anthraquinone, anthraquinone-2-carboxylic acid, and 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone (lapachol). With the paper disc diffusion assay 2-(Hydroxymethyl)anthraquinone exhibited strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. Anthraquinone-2-carboxylic acid, lapachol and metronidazole were less effective, exhibiting moderate anti-Helicobacter pylori activity at 0.1 mg/disc. Amoxicillin and tetracycline were the most potent compounds tested, displaying very strong activity at 0.005 mg/disc. 2-(Hydroxymethyl)anthraquinone exhibited moderate activity at this dose. Tetracycline still had strong activity at 0.001 mg/disc while amoxicillin had little activity at this dose.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (209.87 mM)


关键字: sex pheromone | inhibit | 2(Hydroxymethyl)anthraquinone | 2 (Hydroxymethyl)anthraquinone | Photoremovable | 2-(Hydroxymethyl)anthraquinone | Inhibitor | Chilo infuscatellussnellen | PRPG | controlled-release

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相关库: Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Anti-Infection Compound Library | Natural Product Library | Anti-infective Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途