3-表齐墩果酸 TN1248
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 25499-90-5 | ¥9,870.00 | 询底价 |
1 mg | 25499-90-5 | ¥1,230.00 | 询底价 |
5 mg | 25499-90-5 | ¥3,290.00 | 询底价 |
1 mL | 25499-90-5 | ¥3,820.00 | 询底价 |
10 mg | 25499-90-5 | ¥4,790.00 | 询底价 |
25 mg | 25499-90-5 | ¥7,580.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 3-Epioleanolic acid
描述: 3-Epioleanolic acid 是一种分离自马鞭草的有效成分,具有抗炎作用。
体外活性: In this investigation, the uterotonic properties of extracts from this tree were evaluated using both pregnant and non-pregnant guinea pig uterine smooth muscle in vitro. The extracts were prepared using water modified supercritical carbon dioxide at 400 atm and 80 degrees C. As samples of these extracts displayed positive results when screened for uterotonic activity, gravity column chromatography followed by NMR spectroscopy was performed in an attempt to isolate and elucidate the structures of the compounds that were present in the extract. The extract yielded five known compounds of which only two, viz. oleanonic acid and 3-Epioleanolic acid, displayed uterotonic activity. Receptor binding assays were subsequently performed with 3-Epioleanolic acid to ascertain its mode of action. Bradykinin (30 ng/100 microl) and acetylcholine (1 microg/100 microl) were used as the B2 and cholinergic receptor agonists respectively with icatibant (HOE 140) (30 ng/100 microl) and atropine (60 micro/100 microl) as their corresponding antagonists. 3-Epioleanolic acid was observed to mediate its effect through the cholinergic receptor.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (120.43 mM)
关键字: Inhibitor | 3-Epioleanolic acid | inhibit | 3 Epioleanolic acid | 3Epioleanolic acid
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途