3-表熊果酸 TN1249

Product Introduction
Bioactivity


英文名: 3-Epiursolic acid

描述: 3-Epiursolic Acid 是一种三萜类物质，分离自桃金娘科植物，是组织蛋白酶 L 的竞争性抑制剂（IC50=6.5 μM，Ki=19.5 μM），对 cathepsin B 无明显作用。

体外活性: All three extracts were found to exhibit antiinflammatory activity with the chloroform extract being the most active. Chemical investigations of petroleum ether and chloroform extracts led to the isolation of beta-sitosterol, ursolic acid, oleanolic acid, 3-Epiursolic acid, 3-epioleanolic acid, and minor triterpenoids of derivatives of ursolic acid and oleanolic acids. Chromatographic purification of the methanol extract yielded two iridoid glucosides, verbenalin and hastatoside, a phenylpropanoid glycoside, verbascoside and beta-sitosterol-D-glucoside.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 45 mg/mL (98.53 mM)


关键字: inhibit | Cathepsin | 3 Epiursolic acid | 3-Epiursolic acid | 3-Epiursolic Acid | 3Epiursolic acid | Inhibitor

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相关库: Anti-Tumor Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | Anti-COVID-19 Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途