香橙素 TN1406
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 480-20-6 | ¥7,280.00 | 询底价 |
10 mg | 480-20-6 | ¥1,950.00 | 询底价 |
5 mg | 480-20-6 | ¥1,230.00 | 询底价 |
1 mg | 480-20-6 | ¥463.00 | 询底价 |
25 mg | 480-20-6 | ¥3,730.00 | 询底价 |
50 mg | 480-20-6 | ¥5,330.00 | 询底价 |
1 mL | 480-20-6 | ¥1,090.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Dihydrokaempferol
描述: Dihydrokaempferol (Aromadendrin) 是从紫荆花中分离得到的一种天然产物,诱导凋亡并抑制 Bcl-2 和 Bcl-xL 的表达,可以作为抗关节炎的良好新药候选。
体外活性: Aromadendrin, a flavonol, has been reported to possess a variety of pharmacological activities such as anti-inflammatory, antioxidant, and anti-diabetic properties.?Aromadendrin significantly suppressed LPS-induced excessive production of pro-inflammatory mediators such as nitric oxide (NO) and PGE2.?In accordance, aromadendrin attenuated LPSinduced overexpression iNOS and COX-2.?In addition, aromadendrin significantly suppressed LPS-induced degradation of IκB, which sequesters NF-κB in cytoplasm, consequently inhibiting the nuclear translocation of pro-inflammatory transcription factor NF- κB.?Aromadendrin significantly attenuated LPS-induced activation of JNK, but not ERK and p38, in a concentration-dependent manner.?Aromadendrin exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of JNK in LPS-stimulated RAW 264.7 macrophage cells[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : < 0.1 mg/mL (insoluble)
DMSO : 120 mg/mL (416.31 mM)
关键字: Apoptosis | Dihydrokaempferol | Inhibitor | Bcl-2 Family | inhibit
相关产品: Ziyuglycoside II | GSPT1 degrader-1 | Dihydrorotenone | Asiaticoside | Kinetin riboside | Calcium dobesilate | Decursin | 5-Methoxyuridine | Cholesteryl Hemisuccinate Tris Salt | Tasisulam
相关库: PBCRBS Traditional Chinese Medicine Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Tobacco Monomer Library | Selected Plant-Sourced Compound Library | Inhibitor Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Miao medicine Compound Library | Cuproptosis Compound Library | Covalent Inhibitor Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途