β-生育酚 TN1441

Product Introduction
Bioactivity


英文名: Beta-Tocopherol

描述: Beta-Tocopherol 对由 phorbol 12-myristate 13-acetate (PMA) 诱导的人红白血病细胞 (HEL) 粘附有影响。

体外活性: Adhesion induced by PMA stimulation was prevented by 44.5% by physiological concentrations of alpha-tocopherol. Under the same experimental conditions, Beta-Tocopherol, an analogue of alpha-tocopherol, produced 11% inhibition of adhesion. Cell response gradually increased from 0 to 24 h of alpha-tocopherol treatment. Only a slight time dependency of Beta-Tocopherol inhibition was observed. Another human erythroleukemia cell line (K562) and the human monocyte tumor cell line U937 showed 5.0 and 11.2% inhibition, respectively. Similar to alpha-tocopherol, the protein kinase C inhibitor, Calphostin C, and the MAPK inhibitor, PD98059, prevented PMA-induced cell adhesion. An inhibition of ERK-1 phosphorylation was observed for alpha-tocopherol only in HEL, implying that MAP kinase pathway is involved in this cell line.

存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 75 mg/mL (179.99 mM)


关键字: b-Tocopherol | β-Tocopherol | vitamin E | inhibit | Beta-Tocopherol | Beta Tocopherol | Tyrosinase | Inhibitor | BetaTocopherol | antioxidant

相关产品: Broussonin E | Tizaterkib | Nyasol | trans-Zeatin | Tauroursodeoxycholate sodium | Lidocaine | Piperlongumine | JWG-071 | STE-MEK1(13) | PD98059

相关库: Anti-Tumor Natural Product Library | Tobacco Monomer Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Kinase Inhibitor Library | Cytoskeletal Signaling Pathway Compound Library | Traditional Chinese Medicine Monomer Library | Food as Medicine Compound Library | Gut Microbial Metabolite Library

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