葫芦素A TN1533

Product Introduction
Bioactivity


英文名: Cucurbitacin A

描述: Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase.

体外活性: We unravel here that cucurbitacin I actually induces the co-aggregation of actin with phospho-myosin II. This co-aggregation most probably results from the stimulation of the Rho/ROCK pathway and the direct inhibition of the LIMKinase. We further provide data that suggest that the formation of these co-aggregates is independent of a putative pro-oxidant status of cucurbitacin I.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Cucurbitacin A

相关产品: GSK269962A | RKI-1447 | ROCK-IN-5 | GSK-25 | ROCK-IN-9 | CCG-222740 | Y-33075 dihydrochloride | Netarsudil Dihydrochloride | AT13148 | Verosudil

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途