伽升沃 D TN1674
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 107390-08-9 | ¥1,550.00 | 询底价 |
25 mg | 107390-08-9 | ¥8,580.00 | 询底价 |
10 mg | 107390-08-9 | ¥5,580.00 | 询底价 |
50 mg | 107390-08-9 | ¥11,500.00 | 询底价 |
5 mg | 107390-08-9 | ¥3,880.00 | 询底价 |
1 mL | 107390-08-9 | ¥4,680.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Garcinone D
描述: Garcinone D 是来自山竹的一种呫吨酮,可促进 C17.2 神经干细胞的增殖。它以浓度和时间依赖的方式增加磷酸化信号转导和转录激活因子 3 (p-STAT3)、Cyclin D1 和核因子红细胞 2 相关因子 (Nrf2)、以及血红素加氧酶-1 (HO-1) 的蛋白质水平。
体外活性: Meanwhile, the root bark of the plant furnished six xanthones, namely alpha-mangostin (2), beta-mangostin (3), gamma-mangostin (4), Garcinone D (5), mangostanol (6), and gartanin (7). The hexane and chloroform extracts of the root bark of G. mangostana as well as the hexane extract of the stem bark were found to be active against the CEM-SS cell line. gamma-Mangostin (4) showed good activity with a very low IC(50) value of 4.7 microg/ml, while alpha-mangostin (2), mangostanol (6), and Garcinone D (5) showed significant activities with IC(50) values of 5.5, 9.6, and 3.2 microg/ml, respectively[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (116.69 mM)
关键字: Keap1-Nrf2 | inhibit | Reactive Oxygen Species | Inhibitor | STAT | Garcinone D
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途