匙羹藤苷元 TN1719

Product Introduction
Bioactivity


英文名: Gymnestrogenin

描述: Gymnestrogenin has a dual LXRα±/α2 antagonistic profile.

体外活性: The study disclosed for the first time that individual gymnemic acids are potent and selective antagonists for the β isoform of LXR. Indeed the above activity was shared by the most abundant aglycone gymnemagenin (10) whereas Gymnestrogenin (11) was endowed with a dual LXRα±/β antagonistic profile. Deep pharmacological investigation demonstrated that Gymnestrogenin, reducing the expression of SREBP1c and ABCA1 in vitro, is able to decrease lipid accumulation in HepG2 cells.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Gymnestrogenin

相关产品: BMS-779788 | GSK2033 | BE1218 | SR9238 | Saikosaponin A | Gymnemagenin | RGX-104 hydrochloride | GW3965 hydrochloride | Rovazolac | LXR-623

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途