异七叶皂苷 IB TN1777
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 219944-46-4 | ¥547.00 | 询底价 |
5 mg | 219944-46-4 | ¥1,370.00 | 询底价 |
50 mg | 219944-46-4 | 面议 | 询底价 |
10 mg | 219944-46-4 | ¥1,980.00 | 询底价 |
1 mL | 219944-46-4 | ¥2,390.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Isoescin IB
描述: Isoescin IB 是 Escin IB 的异构体,两者是 Escin 中的主要活性成分。
体内活性: Five groups of Wistar rats (n=6 per group) were treated with either an intravenous (IV) dose (2.78mg/kg) of sodium escinate (corresponding to 0.5mg/kg of Escin IB and 0.5mg/kg of Isoescin IB), an IV dose (0.5mg/kg) and an oral dose (4mg/kg) of pure Escin IB or Isoescin IB. The administration of sodium escinate, which contains the two isomers, gave rise to higher terminal phase half-life (t1/2) and mean residence time (MRT) values for both Escin IB and Isoescin IB compared to the corresponding compounds administered alone. The absorption of Escin IB and Isoescin IB was very poor, with the oral bioavailability (F) values of <2% observed for both compounds. The two compounds were found to isomerize in vivo, wherein the conversion of Escin IB to Isoescin IB was much easier than that of Isoescin IB to Escin IB[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 100 mg/mL (88.40 mM)
关键字: Escin | inhibit | Inhibitor | Escin IB | Isoescin IB
相关库: Rare Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途