化合物Kanzonol C TN1832
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 151135-82-9 | ¥6,300.00 | 询底价 |
5 mg | 151135-82-9 | ¥5,250.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Kanzonol C
描述: Kanzonol C has antimicrobial activity, it also shows potent PTP1B inhibitory activity (IC50 value of 0.31-0.97uM). Kanzonol C has chemopreventive activity,it shows the inhibition of matrix metalloproteinase (MMP)-2 secretion from brain tumor-derived glioblastoma cells.
体外活性: Based on the bioactivities of licorice, these compounds were screened using cell- or enzyme-based bioassay methods. A total of 11 compounds exhibited potent cytotoxic activities against three human cancer cell lines (HepG2, SW480 and MCF7), while showed little toxicity on human normal cell lines LO2 and HEK293T. A number of chalcones showed remarkable anti-inflammatory activities. Among them, 2 (licochalcone B, IC50 8.78μM), 10 (licoagrochalcone C, IC50 9.35μM) and 13 (licochalcone E, IC50 9.09μM) exhibited the most potent inhibitory activities on LPS-induced NO production, whereas 1, 8, 10, 12 and 13 (IC50 13.9, 7.27, 2.44, 6.67 and 3.83μM) showed potent inhibitory activities on NF-κB transcription[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Kanzonol C
相关产品: Sodium Houttuyfonate | Hydrangenol | yangonin | 4-methoxylonchocarpin | SM-7368 | Ginsenoside Rb3 | Wedelolactone | Ganoderic acid C1 | SIM-688 | CTP-NBD
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途