赤芝酸 C TN1881

Product Introduction
Bioactivity


英文名: Lucidenic acid C

描述: Lucidenic acid C has anti-invasive effect, it shows significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.

体外活性: Triterpenoid components in the ethanol extract of G. lucidum (YK-02) were separated by means of a semi-preparative RP HPLC. Four major peaks were separated and crystallized from triterpenoids fraction, and were identified as lucidenic acid A, lucidenic acid B, Lucidenic acid C, and lucidenic acid N according to their spectroscopic values of (1)H NMR and MS. Treatment of the lucidenic acids (50 microM) in the presence of 200 nM phorbol 12-myristate 13-acetate (PMA) after 24 h of incubation all resulted in significant inhibitory effects on PMA-induced MMP-9 activity and invasion of HepG(2 )cells.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Lucidenic acid C

相关产品: BR351 | TNO211 | DB04760 | Histatin 5 acetate | MMP13-IN-4 | Picroside I | GI254023X | Glucosamine | T-5224 | Cedrelone

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途