赤芝酸D TN1882
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 98665-16-8 | ¥9,570.00 | 询底价 |
1 mg | 98665-16-8 | ¥3,820.00 | 询底价 |
10 mg | 98665-16-8 | ¥14,500.00 | 询底价 |
25 mg | 98665-16-8 | ¥25,400.00 | 询底价 |
200 mg | 98665-16-8 | ¥89,970.00 | 询底价 |
50 mg | 98665-16-8 | ¥39,100.00 | 询底价 |
100 mg | 98665-16-8 | ¥59,980.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Lucidenic acid D
描述: Lucidenic acid D2 is a nartural product from G. lucidum AF.
体外活性: Here, we showed that triterpenes-rich extract of antlered form of G. lucidum (G. lucidum AF) induces TNFα± production in monocytic THP-1 cells. Furthermore, the extract also synergized with lipopolysaccharide (LPS) to induce TNFα± production in THP-1 cells, suggesting an immunostimulatory role of triterpenes-rich extract of G. lucidum AF. Notably, the extract enhanced LPS-induced phosphorylation of p38 mitogen-activated protein kinase (MAPK), while it suppressed LPS-induced phosphorylation of c-Jun N-terminal kinase (JNK) MAPK. p38 Inhibitor suppressed TNFα± production, while JNK inhibitor enhanced TNFα± production, implying that synergistic effect of the extract may work by modulating p38 and JNK MAPKs. Moreover, we found that the triterpenes-rich extract of G. lucidum AF contains high amounts of lucidenic acids. Lucidenic acid A, Lucidenic acid F and Lucidenic acid D2, which seem to dominantly exist in the extract, were purified from the triterpenes-rich extract. We also identified Lucidenic acid-A and -F as modulators of JNK and p38, respectively.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Lucidenic acid D
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途