五味子酯 D TN2186

Product Introduction
Bioactivity


英文名: Schisantherin D

描述: Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110.

体外活性: Seven of these compounds (1, 6, 8-12) were active as anti-HIV agents. Gomisin G (11) exhibited the most potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively. Schisantherin D (6), kadsuranin (8), and schisandrin C (10) showed good activity with EC50 values of 0.5, 0.8, and 1.2 micrograms/mL, and TI values of 110, 56, and 33.3, respectively. Ten related synthetic biphenyl compounds, five variously substituted bismethylenedioxy, dimethoxy, and dimethoxycarbonyl isomers (18-22) and five brominated derivatives (23-27) also were evaluated for inhibitory activity against HIV-1 replication in acutely infected H9 cells.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Schisantherin D

相关产品: Vicriviroc maleate | Licoarylcoumarin | Elvitegravir | Calanolide E | TAK-220 | Helichrysetin | Oleanonic acid | ONX-0914 | Oleoside | 9-Aminoacridine

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途