皱唐松草宁碱 TN2271
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 22226-73-9 | ¥14,300.00 | 询底价 |
1 mL | 22226-73-9 | ¥17,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Thalrugosaminine
描述: Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. Thalrugosaminine possesses hypotensive activity in rabbits and is active against Mycobacterium smegmatis.
体外活性: A total of three alkaloid compounds were isolated from the DCM: MeOH extract of roots of T. minus using silica gel column chromatography. Structural elucidation of the isolated compounds was done by using spectroscopic techniques like mass spectrometry and NMR spectroscopy. Pathogens were isolated from cases of bovine mastitis and identified by using 16S rRNA gene sequencing. The broth micro-dilution method was used to evaluate the antibacterial activities of DCM: MeOH extract and isolated compounds against mastitis pathogens. The three isolated compounds were identified as benzylisoquinoline alkaloids (1) 5'-Hydroxythalidasine, (2) Thalrugosaminine and (3) O-Methylthalicberine. Compounds (2) and (3) are reported for the first time from the roots of T. minus. Five mastitis pathogens viz., Staphylococcus xylosus, Staphylococcus lentus, Staphylococcus equorum, Enterococcus faecalis and Pantoea agglomerans were identified on the basis of sequence analysis of isolates using the nucleotide BLAST algorithm. This study reports for the first time the isolation and molecular characterization of mastitis pathogens from Kashmir valley, India. The DCM: MeOH extract exhibited broad spectrum antibacterial activities that varied between the bacterial species (MIC=250-500μg/ml). 5'-Hydroxythalidasine and Thalrugosaminine showed promising antibacterial activity with MIC values of 64-128μg/ml while Staphylococcus species were found to be the most sensitive strains[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Thalrugosaminine
相关产品: (2S)-2'-Methoxykurarinone | 2-Acetoxy-3-deacetoxycaesaldekarin E | Totarol | Neochamaejasmine B | Miconazole | Econazole | 5-Heneicosylresorcinol | Albaspidin AA | 15-Hydroxydehydroabietic acid | 2-Methoxyphenalen-1-one
皱唐松草宁碱 TN2271信息由TargetMol中国为您提供,如您想了解更多关于皱唐松草宁碱 TN2271报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途