化合物 TN6547 TN6547
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 550-43-6 | ¥2,860.00 | 询底价 |
5 mg | 550-43-6 | ¥2,760.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Angustifoline
描述: Angustifoline has activity against gram-positive bacteria. It inhibits human colon cancer cell growth by inducing autophagy along with mitochondrial-mediated apoptosis, suppression of cell invasion and migration and stimulating G2/M cell cycle arrest.
体外活性: Twelve lupine alkaloids, eight from Lupinus polyphyllus (Lindl), were tested in feeding bioassays against sixth instar spruce budworm, Choristoneura fumiferana (Clemens). METHODS AND RESULTS: Feeding deterrence was found in the alkaloid fraction of L. polyphyllus extracts. Eight lupine alkaloids shown to be present in the extract were tested at the rate of 25 μg per feeding disc. Of these compounds, 13-trans-cinnamoyloxylupanine and 13- tigloyloxylupanine were highly deterrent, whereas lupanine, sparteine, 13-hydroxylupanine, tetrahydrorhombifoline, Angustifoline, and 17-oxolupanine, were not. Four alkaloids not present in L. polyphyllus, lupinine, epilupinine, α-isolupanine, and lupinyl-trans-cinnamate, were not active at 25 μg per feeding disc. CONCLUSIONS: Clearly, there is wide variability in the response of spruce budworm larvae, which are not adapted to feeding on alkaloids, to various alkaloids within the same structural class. If this variability in response is general among herbivores, perhaps the presence of an alkaloid is not significant with regard to defense, whereas diversity in structure of alkaloids may deter generalist grazers.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Angustifoline
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途