化合物 TN6690 TN6690

Product Introduction
Bioactivity


英文名: Cyclo(Tyr-Val)

描述: Cyclo(Tyr-Val) 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6690，CAS号为 21754-25-6。

体外活性: In order to provide more natural antifouling compounds, marine bacterium Pseudomonas putida isolated from the sponge Haliclona sp. was explored to test its anti-diatom compounds. METHODS AND RESULTS: The strain was identified by colonial morphology, scanning electron microscope (SEM) and 16S rDNA sequence analysis. The separation procedure was guided by bioactive (Anti-diatom) and chemical (TLC, DAD-HPLCand 1H NMR) analysis, and their structures were elucidated by spectrographic techniques. The anti-diatom activity of all purified compounds was assayed. Strain 272 isolated from the sponge Haliclona sp. was identified as Pseudomonas putida. Six diketopiperazine compounds were isolated from the culture of this strain and their structures were determined as cyclo(Leu-Pro) (1), cyclo (Leu-Ala) (2), cyclo(Phe-Ala) (3), Cyclo(Tyr-Val) (4), cyclo(Ala-Tyr) (5), cyclo(Ala-Trp) (6); Compounds 3 and 6 displayed significant anti-diatom activity with the inhibitory rate of 50% and 85% at the concentration of 50 microg/mL, respectively. CONCLUSIONS: The anti-diatom compounds isolated from marine bacterium Pseudomonas putida were cyclo (Phe-Ala) and cyclo (Ala-Trp).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Cyclo(TyrVal) | Cyclo(Tyr-Val) | Cyclo(Tyr Val)

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途