化合物Fz7-21 TP1263

Product Introduction
Bioactivity


英文名: Fz7-21

描述: Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) 是一种 Frizzled 7 (FZD 7) 受体的肽抑制剂，能够选择性的与FZD7 CRD 亚类结合。它还阻断了WNT3A 介导的β-catenin 在小鼠L 细胞中的稳定作用。它对外源性WNT3A 刺激和转染WNT3A 或WNT1的HEK293细胞Wnt/β-catenin 信号传导有损伤。

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mM


关键字: lipid-binding groove | FZD7 | Wnt | Fz7 21 | Wnt–β-catenin | Fz-7-21 | conformation | FZD7 CRD | intestinal organoids | Inhibitor | Fz721 | inhibit | Fz7-21

相关产品: SSTC3 | β-catenin/CBP-IN-1 | PNU-74654 | Pyrvinium pamoate | Ginkgetin | K-756 | ISX-9 | BML-284 | Gossypolone | IWP-O1

相关库: Anti-Prostate Cancer Compound Library | Wnt/Hedgehog/Notch Compound Library | Neuronal Differentiation Compound Library | Anti-Ovarian Cancer Compound Library | Neural Regeneration Compound Library | Peptide Compound Library | Anti-Colorectal Cancer Compound Library | Cytoskeletal Signaling Pathway Compound Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途