米罗那非二盐酸盐 TQ0126

Product Introduction
Bioactivity


英文名: Mirodenafil dihydrochloride

描述: Mirodenafil dihydrochloride 是一种磷酸二酯酶5（PDE-5）抑制剂，可作用于勃起功能紊乱的研究。

体内活性: Mirodenafil, in doses of 50 or 100 mg, significantly improved erectile function and was well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities [1]. The concurrent administration of mirodenafil with alcohol was not associated with clinically significant hemodynamic changes in these healthy male volunteers in Korea. The pharmacokinetics of mirodenafil were not significantly altered by this concurrent administration. Mirodenafil administered with alcohol had a tolerability profile comparable to that of mirodenafil alone [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (82.7 mM)


关键字: Inhibitor | Wnt | Beta catenin | Mirodenafil Dihydrochloride | MRC-5 cells | SK3530 Dihydrochloride | Mirodenafil dihydrochloride | Glucocorticoid Receptor | Phosphodiesterase (PDE) | NIH3T3 | erectile dysfunction | Alzheimer’s disease | inhibit | SK 3530 | SH-SY5Y | Mirodenafil | SK-3530 | SK-3530 Dihydrochloride | β-catenin | systemic sclerosis | SK 3530 Dihydrochloride | Apoptosis | HT-22 cells | SK3530 | fibrosis

相关产品: 4,5-Dimethoxycanthin-6-one | ML-030 | TBA-7371 | Pimobendan | ATX inhibitor 1 | Acefylline | MK-0873 | Glaucine | Enpp/Carbonic anhydrase-IN-2 | N-Methylbenzamide

相关库: Drug Repurposing Compound Library | Approved Drug Library | FDA-Approved & Pharmacopeia Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Metabolism Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途