他托布林 TQ0141
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 228266-40-8 | ¥9,180.00 | 询底价 |
5 mg | 228266-40-8 | ¥1,980.00 | 询底价 |
25 mg | 228266-40-8 | ¥6,920.00 | 询底价 |
100 mg | 228266-40-8 | ¥14,100.00 | 询底价 |
2 mg | 228266-40-8 | ¥1,270.00 | 询底价 |
1 mL | 228266-40-8 | ¥2,390.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Taltobulin
描述: Taltobulin (HTI-286) is a potent tubulin inhibitor.
体外活性: HTI-286 significantly inhibited the proliferation of all three hepatic tumor cell lines (mean IC50: 2 nmol/L) in vitro. No decrease in viable primary human hepatocytes (PHH) was detected under HTI-286 exposure [1]. In all cell lines tested, HTI-286 was a potent inhibitor of proliferation and induced marked increases in apoptosis [2].
体内活性: Intravenous administration of HTI-286 significantly inhibited tumor growth in vivo (rat allograft model) [1]. HTI-286 significantly inhibited the growth of PC-3 and LNCaP xenografts and retained potency in PC-3dR tumors. Simultaneous castration plus HTI-286 therapy was superior to sequential treatment in the LNCaP model [2].
存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 95 mg/mL (200.57 mM)
关键字: HTI 286 | SPA 110 | SPA110 | Taltobulin | HTI286
相关产品: Verubulin hydrochloride | Colchicine | Auristatin F | Lys-SMCC-DM1 | TAI-1 | Tubulysin D | C004019 | GSK-3 inhibitor 3 | Lexibulin | SS28
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途